D2 Multi Instances Multi Players


So, I know theres already multiple instance hacks for D2. What I'm thinking is that I want to run it twice, one on each monitor(attached to the same machine of course), run two USB keyboards and two USB mice, and play two player on one machine. I don't know how the multi mice and keyboards would run with windows other than they would both control at the same time. I'm wondering if I could split them and have one set command each instance. If not, I could also try out something like a gamepad. I'm starting some research and am hoping I can get some advice. Forgive me if someone already did this but I couldn't find anything in google or these forums. Thanks.